STRINGSTRING
ompA protein (Escherichia coli K12 MG1655) - STRING interaction network
"ompA" - Outer membrane protein A in Escherichia coli K12 MG1655
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ompAOuter membrane protein A; Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (346 aa)    
Predicted Functional Partners:
ompC
Outer membrane protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family (367 aa)
   
  0.998
rpsB
30S ribosomal protein S2; Required for ribosomal protein S1 to bind to the 30S subunit (241 aa)
     
 
  0.998
ompF
Outer membrane protein F; Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2; Belongs to the Gram-negative porin family (362 aa)
   
  0.997
rpsI
30S ribosomal protein S9; The C-terminal tail plays a role in the affinity of the 30S P site for different tRNAs. Mutations that decrease this affinity are suppressed in the 70S ribosome (130 aa)
     
 
  0.990
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5’-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome; Belongs to the universal ribosomal protein uL4 family (201 aa)
     
 
  0.989
rpsU
30S ribosomal protein S21; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family (71 aa)
     
 
  0.989
rpmH
50S ribosomal protein L34; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL34 family (46 aa)
     
      0.989
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family (75 aa)
       
      0.989
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity); Belongs to the universal ribosomal protein uS3 family (233 aa)
       
      0.989
rpmI
50S ribosomal subunit protein A; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bL35 family (65 aa)
       
      0.989
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (20%) [HD]