STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yccTUPF0319 family protein; Belongs to the UPF0319 family. (220 aa)    
Predicted Functional Partners:
yccF
DUF307 family inner membrane protein.
      
 0.632
yobB
C-N hydrolase family protein.
      
 0.624
yccS
Putative transporter, FUSC superfamily inner membrane protein.
     
 0.544
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.543
yccU
Putative CoA-binding protein.
  
    0.543
ycbZ
Putative ATP-dependent protease; Protein involved in proteolysis.
      
 0.519
secE
Preprotein translocase membrane subunit; Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY; Belongs to the SecE/SEC61-gamma family.
      
 0.518
yhbT
SCP-2 sterol transfer family protein; Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.
      
 0.510
csgF
Curli nucleation outer membrane protein; May be involved in the biogenesis of curli organelles.
   
  
 0.479
ynfB
UPF0482 family putative periplasmic protein.
      
 0.409
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.