node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hspQ | lptC | b0966 | b3199 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.723 |
hspQ | mscM | b0966 | b4159 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | 0.693 |
hspQ | ompC | b0966 | b2215 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | Outer membrane porin protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane. (Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA- EC536-mediated toxicity; Belongs to the Gram-negative porin family. | 0.591 |
hspQ | ompN | b0966 | b1377 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | Outer membrane pore protein N, non-specific; Forms pores that allow passive diffusion of small molecules across the outer membrane (By similarity). Non-specific porin. | 0.615 |
hspQ | rlmI | b0966 | b0967 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | 23S rRNA m(5)C1962 methyltransferase, SAM-dependent; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. Methylation occurs before assembly of 23S rRNA into 50S subunits; Belongs to the methyltransferase superfamily. RlmI family. | 0.865 |
hspQ | tusE | b0966 | b0969 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | mnm(5)-s(2)U34-tRNA 2-thiolation sulfurtransferase; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD. | 0.679 |
hspQ | wecD | b0966 | b3790 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.749 |
hspQ | wecF | b0966 | b4481 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | TDP-Fuc4NAc:lipidIIFuc4NAc transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.753 |
hspQ | wzxE | b0966 | b3792 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | O-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC)). Could also mediate the translocation of Und-PP-GlcNAc. | 0.686 |
hspQ | yccU | b0966 | b0965 | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | Putative CoA-binding protein. | 0.662 |
lptC | hspQ | b3199 | b0966 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | 0.723 |
lptC | mscM | b3199 | b4159 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | 0.586 |
lptC | ompC | b3199 | b2215 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Outer membrane porin protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane. (Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA- EC536-mediated toxicity; Belongs to the Gram-negative porin family. | 0.658 |
lptC | ompN | b3199 | b1377 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | Outer membrane pore protein N, non-specific; Forms pores that allow passive diffusion of small molecules across the outer membrane (By similarity). Non-specific porin. | 0.598 |
lptC | wecD | b3199 | b3790 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. | 0.693 |
lptC | wecF | b3199 | b4481 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | TDP-Fuc4NAc:lipidIIFuc4NAc transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.699 |
lptC | wzxE | b3199 | b3792 | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | O-antigen translocase; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC)). Could also mediate the translocation of Und-PP-GlcNAc. | 0.637 |
mscM | hspQ | b4159 | b0966 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Heat shock protein involved in degradation of mutant DnaA; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress. | 0.693 |
mscM | lptC | b4159 | b3199 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Periplasmic membrane-anchored LPS-binding protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.586 |
mscM | ompC | b4159 | b2215 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Outer membrane porin protein C; Forms pores that allow passive diffusion of small molecules across the outer membrane. (Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA- EC536-mediated toxicity; Belongs to the Gram-negative porin family. | 0.722 |