STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfcCPutative O-antigen capsule production periplasmic protein; To E.coli YjbG. (248 aa)    
Predicted Functional Partners:
gfcD
Putative O-antigen capsule production periplasmic protein.
  
 0.996
gfcB
O-antigen capsule production lipoprotein; Putative regulator.
  
 0.995
gfcE
Putative O-antigen capsule outer membrane auxillary protein export channel; May be involved in polysaccharide transport; Belongs to the BexD/CtrA/VexA family.
  
  
 0.975
gfcA
O-antigen capsule production threonine-rich inner membrane protein.
  
  
 0.954
etk
Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family.
  
  
 0.940
etp
O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.937
yjbH
DUF940 family extracellular polysaccharide protein.
   
 0.864
yfcL
Uncharacterized protein.
  
   
 0.674
wza
Colanic acid export protein; Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium.
  
  
 0.634
ftsN
Essential cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable). Required for full FtsI activity. Required for recruitment of AmiC to the septal ring. Belongs to the FtsN family.
  
   
 0.634
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (28%) [HD]