STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfcBO-antigen capsule production lipoprotein; Putative regulator. (214 aa)    
Predicted Functional Partners:
gfcC
Putative O-antigen capsule production periplasmic protein; To E.coli YjbG.
  
 0.995
gfcD
Putative O-antigen capsule production periplasmic protein.
  
 0.991
gfcA
O-antigen capsule production threonine-rich inner membrane protein.
  
  
 0.959
gfcE
Putative O-antigen capsule outer membrane auxillary protein export channel; May be involved in polysaccharide transport; Belongs to the BexD/CtrA/VexA family.
  
  
 0.933
etp
O-antigen capsule forming protein-tyrosine-phosphatase; Dephosphorylates etk; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 0.929
etk
Tyrosine-protein kinase, role in O-antigen capsule formation; Protein involved in protein modification process; Belongs to the etk/wzc family.
  
  
 0.911
yjbH
DUF940 family extracellular polysaccharide protein.
   
 0.900
yjbG
Extracellular polysaccharide export OMA protein; To E.coli YmcB.
     0.807
ycgR
Flagellar velocity braking protein, c-di-GMP-regulated; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. When bound to c-di-GMP it binds to elements of the flagellar motor (MotA and/or FliG and FliM , binding to FliM also occurs in the absence of c-di-GMP), causing the motor to slow down. Thus, increasing levels of c-di-GMP lead to decreased motility. Probably binds 1 c-di-GMP dimer per subunit.
  
     0.628
wzzE
Entobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC)).
      
 0.624
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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