node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dps | osmE | b0812 | b1739 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | 0.736 |
dps | sra | b0812 | b1480 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein | 0.855 |
dps | wrbA | b0812 | b1004 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH | 0.826 |
dps | yccJ | b0812 | b1003 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | annotation not available | 0.778 |
dps | yeaG | b0812 | b1783 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | Protein kinase, endogenous substrate unidentified; Belongs to the PrkA family | 0.762 |
dps | ygaU | b0812 | b2665 | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | 0.822 |
mlrA | sbcB | b2127 | b2011 | Merr family transcriptional regulator, activator of the csg genes; Activates transcription of csgD, the master regulator of biofilm formation, by binding to its promoter region Also controls the transcription of cadC and ibaG . Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA | Exodeoxyribonuclease i; Degrades single-stranded DNA (ssDNA) in a highly processive manner . Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage of DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease or AP lyase | 0.828 |
mlrA | wrbA | b2127 | b1004 | Merr family transcriptional regulator, activator of the csg genes; Activates transcription of csgD, the master regulator of biofilm formation, by binding to its promoter region Also controls the transcription of cadC and ibaG . Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA | Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH | 0.909 |
mlrA | yecE | b2127 | b1868 | Merr family transcriptional regulator, activator of the csg genes; Activates transcription of csgD, the master regulator of biofilm formation, by binding to its promoter region Also controls the transcription of cadC and ibaG . Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA | DUF72 domain-containing protein YecE; Belongs to the UPF0759 family | 0.916 |
osmE | dps | b1739 | b0812 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | 0.736 |
osmE | sra | b1739 | b1480 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein | 0.803 |
osmE | wrbA | b1739 | b1004 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH | 0.860 |
osmE | yccJ | b1739 | b1003 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | annotation not available | 0.804 |
osmE | yeaG | b1739 | b1783 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | Protein kinase, endogenous substrate unidentified; Belongs to the PrkA family | 0.733 |
osmE | ygaU | b1739 | b2665 | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+) . May be involved in the regulation of peptidoglycan cross-linking | 0.731 |
sbcB | mlrA | b2011 | b2127 | Exodeoxyribonuclease i; Degrades single-stranded DNA (ssDNA) in a highly processive manner . Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage of DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease or AP lyase | Merr family transcriptional regulator, activator of the csg genes; Activates transcription of csgD, the master regulator of biofilm formation, by binding to its promoter region Also controls the transcription of cadC and ibaG . Part of a signaling cascade that regulates curli biosynthesis. The cascade is composed of two c-di-GMP control modules, in which c-di-GMP controlled by the DgcE/PdeH pair (module I) regulates the activity of the DgcM/PdeR pair (module II), which in turn regulates activity of the transcription factor MlrA | 0.828 |
sbcB | wrbA | b2011 | b1004 | Exodeoxyribonuclease i; Degrades single-stranded DNA (ssDNA) in a highly processive manner . Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage of DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease or AP lyase | Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH | 0.874 |
sbcB | yecE | b2011 | b1868 | Exodeoxyribonuclease i; Degrades single-stranded DNA (ssDNA) in a highly processive manner . Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage of DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease or AP lyase | DUF72 domain-containing protein YecE; Belongs to the UPF0759 family | 0.900 |
sra | dps | b1480 | b0812 | Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein | Stationary phase nucleoid protein that sequesters iron and protects dna from damage; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects [...] | 0.855 |
sra | osmE | b1480 | b1739 | Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein | Osmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress | 0.803 |