node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ghrA | ycdX | b1033 | b1034 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.911 |
ghrA | ycdY | b1033 | b1035 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.812 |
ghrA | ycdZ | b1033 | b1036 | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | DUF1097 family inner membrane protein. | 0.690 |
hybE | narW | b2992 | b1466 | Hydrogenase 2-specific chaperone; Member of hyb operon. | Nitrate reductase 2 (NRZ), delta subunit (assembly subunit); Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2. | 0.524 |
hybE | ycdY | b2992 | b1035 | Hydrogenase 2-specific chaperone; Member of hyb operon. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.781 |
lpoA | ycdY | b3147 | b1035 | OM lipoprotein stimulator of MrcA transpeptidase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Stimulates transpeptidase activity of PBP1a in vitro. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.762 |
lpoA | ydbH | b3147 | b1381 | OM lipoprotein stimulator of MrcA transpeptidase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Stimulates transpeptidase activity of PBP1a in vitro. | Putative membrane-anchored protein, function unknown. | 0.716 |
lpoA | yhfK | b3147 | b3358 | OM lipoprotein stimulator of MrcA transpeptidase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Stimulates transpeptidase activity of PBP1a in vitro. | Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. | 0.653 |
lpoA | yhjJ | b3147 | b3527 | OM lipoprotein stimulator of MrcA transpeptidase; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Stimulates transpeptidase activity of PBP1a in vitro. | Putative periplasmic M16 family chaperone; Belongs to the peptidase M16 family. | 0.723 |
narW | hybE | b1466 | b2992 | Nitrate reductase 2 (NRZ), delta subunit (assembly subunit); Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2. | Hydrogenase 2-specific chaperone; Member of hyb operon. | 0.524 |
narW | torD | b1466 | b0998 | Nitrate reductase 2 (NRZ), delta subunit (assembly subunit); Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2. | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | 0.628 |
narW | ycdY | b1466 | b1035 | Nitrate reductase 2 (NRZ), delta subunit (assembly subunit); Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.810 |
torD | narW | b0998 | b1466 | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | Nitrate reductase 2 (NRZ), delta subunit (assembly subunit); Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase 2. | 0.628 |
torD | ycdX | b0998 | b1034 | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.545 |
torD | ycdY | b0998 | b1035 | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.786 |
ycdX | ghrA | b1034 | b1033 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | 0.911 |
ycdX | torD | b1034 | b0998 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | TorA-maturation chaperone; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor. | 0.545 |
ycdX | ycdY | b1034 | b1035 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.998 |
ycdX | ycdZ | b1034 | b1036 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | DUF1097 family inner membrane protein. | 0.845 |
ycdY | ghrA | b1035 | b1033 | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. | 0.812 |