clsC protein (Escherichia coli K12 MG1655) - STRING interaction network

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clsC

Stationary phase cardiolipin synthase 3; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE) (473 aa)

Predicted Functional Partners:

ymdB

0.991

pgpA

0.949

pgpC

0.926

pgpB

0.912

clsB

0.904

clsA

0.900

pgsA

0.848

pssA

0.825

ynjF

0.815

ymdA

0.776

Your Current Organism:

Escherichia coli K12 MG1655

NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
clsA	clsB	b1249	b0789	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	0.906
clsA	clsC	b1249	b1046	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Stationary phase cardiolipin synthase 3; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE)	0.900
clsA	pgpA	b1249	b0418	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Phosphatidylglycerophosphatase a; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	0.964
clsA	pgpB	b1249	b1278	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Phosphatidylglycerophosphatase b; Catalyzes the dephosphorylation of diacylglycerol diphosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG). Also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate. Can also use lysophosphatidic acid (LPA) and phosphatidylglycerophosphate as substrates. The pattern of activities varies according to subcellular location, PGP phosphatase activity is higher in the cytoplasmic membrane, whereas PA and LPA phosphatase activities are [...]	0.938
clsA	pgpC	b1249	b2560	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Phosphatidylglycerophosphatase c, membrane bound; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	0.948
clsA	pgsA	b1249	b1912	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids	0.899
clsA	pssA	b1249	b2585	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process	0.873
clsA	ymdB	b1249	b1045	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	2'-O-acetyl-ADP-ribose deacetylase, regulator of RNase III activity; Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate . Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation . Overexpression inhibits biofilm formation via an RNase III-independent pathway. This inhibition is RpoS-dependent . Overexpression also results in increased susceptibility to apramycin	0.560
clsA	ynjF	b1249	b1758	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	Cdp-alcohol phosphatidyltransferase family inner membrane protein; Inner membrane protein YnjF; Putative cytochrome oxidase	0.664
clsB	clsA	b0789	b1249	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	0.906
clsB	clsC	b0789	b1046	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Stationary phase cardiolipin synthase 3; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE)	0.904
clsB	pgpA	b0789	b0418	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Phosphatidylglycerophosphatase a; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	0.979
clsB	pgpB	b0789	b1278	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Phosphatidylglycerophosphatase b; Catalyzes the dephosphorylation of diacylglycerol diphosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG). Also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate. Can also use lysophosphatidic acid (LPA) and phosphatidylglycerophosphate as substrates. The pattern of activities varies according to subcellular location, PGP phosphatase activity is higher in the cytoplasmic membrane, whereas PA and LPA phosphatase activities are [...]	0.959
clsB	pgpC	b0789	b2560	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Phosphatidylglycerophosphatase c, membrane bound; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	0.955
clsB	pgsA	b0789	b1912	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids	0.822
clsB	pssA	b0789	b2585	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	CDP-diacylglycerol--serine O-phosphatidyltransferase; Phosphatidylserine synthase; phospholipid synthesis; Protein involved in phospholipid biosynthetic process	0.790
clsB	ymdB	b0789	b1045	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	2'-O-acetyl-ADP-ribose deacetylase, regulator of RNase III activity; Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate . Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation . Overexpression inhibits biofilm formation via an RNase III-independent pathway. This inhibition is RpoS-dependent . Overexpression also results in increased susceptibility to apramycin	0.733
clsB	ynjF	b0789	b1758	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	Cdp-alcohol phosphatidyltransferase family inner membrane protein; Inner membrane protein YnjF; Putative cytochrome oxidase	0.723
clsC	clsA	b1046	b1249	Stationary phase cardiolipin synthase 3; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE)	Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	0.900
clsC	clsB	b1046	b0789	Stationary phase cardiolipin synthase 3; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE)	Cardiolipin synthase a/b; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Can also catalyze phosphatidyl group transfer to water to form phosphatidate	0.904

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