STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
opgCOPG biosynthetic transmembrane succinyltransferase; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (385 aa)    
Predicted Functional Partners:
opgB
OPG periplasmic biosynthetic phosphoglycerol transferases I (membrane-bound) and II (soluble); Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones. Belongs to the OpgB family.
  
  
 0.966
opgG
OPG biosynthetic periplasmic beta-1,6 branching glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family.
  
  
 0.875
opgH
OPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
  
  
 0.860
rcsD
Phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.
  
  
 0.772
wecH
O-acetyltransferase for enterobacterial common antigen (ECA); Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. Catalyzes the acetylation of both cyclic ECA (ECA(CYC)) and phosphoglyceride-linked ECA (ECA(PG)); Belongs to the acyltransferase 3 family.
 
   
 0.767
fes
Enterobactin/ferrienterobactin esterase; Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use; Belongs to the Fes family.
  
  
 0.747
ampE
Ampicillin resistance inner membrane protein; Putative signaling protein in beta-lactamase regulation. AmpE seems not to act as a direct sensor for beta-lactams.
  
     0.728
ypfG
DUF1176 family protein.
  
     0.722
aroM
AroM family protein; This protein of unknown function is encoded by a gene that cotranscribes with the aroL gene, which codes for shikimate kinase II.
  
     0.693
opgE
OPG biosynthetic transmembrane phosphoethanolamine transferase; Catalyzes the addition of a phosphoethanolamine moiety to the osmoregulated periplasmic glucan (OPG) backbone.
  
  
 0.681
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.