STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yceBannotation not available (186 aa)    
Predicted Functional Partners:
ycdY
Redox enzyme maturation protein (remp) chaperone for ycdx; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process
  
   
 0.807
rcsF
Outer membrane lipoprotein rcsf; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division
  
   
 0.768
yfeY
annotation not available
  
     0.719
ydbH
annotation not available
  
   
 0.706
lpoA
Outer membrane lipoprotein - activator of mrca activity; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Stimulates transpeptidase activity of PBP1a in vitro
  
   
 0.695
ybjN
Negative regulator of motility; Uncharacterized protein YbjN; Putative sensory transduction regulator
  
   
 0.690
yhdP
annotation not available
  
   
 0.677
yrfF
Inner membrane protein - inhibits the rcs signaling pathway; Putative membrane protein IgaA homolog; Putative dehydrogenase
  
     0.670
yidR
annotation not available
  
     0.665
mdtH
Mfs transporter, dha1 family, multidrug resistance protein; Confers resistance to norfloxacin and enoxacin
     
 0.658
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.