node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dinI | mdtH | b1061 | b1065 | DNA damage-inducible protein I; Involved in SOS regulation. Inhibits RecA by preventing RecA to bind ssDNA. Can displace ssDNA from RecA. | Multidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin. | 0.738 |
emrD | emrK | b3673 | b2368 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | 0.795 |
emrD | mdtA | b3673 | b2074 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system, subunit A; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.530 |
emrD | mdtG | b3673 | b1053 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Putative drug efflux system protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.839 |
emrD | mdtH | b3673 | b1065 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin. | 0.801 |
emrD | mdtK | b3673 | b1663 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system transporter; Multidrug efflux pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP). Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium. Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing [...] | 0.819 |
emrD | mdtL | b3673 | b3710 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system protein; Confers resistance to chloramphenicol. Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily. | 0.527 |
emrD | mdtM | b3673 | b4337 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Multidrug efflux system protein; Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP; Belongs to the major facilitator superfamily. | 0.524 |
emrD | mdtP | b3673 | b4080 | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | Outer membrane factor of efflux pump; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.417 |
emrK | emrD | b2368 | b3673 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system protein; Multidrug resistance pump that participates in a low energy shock adaptive response; Belongs to the major facilitator superfamily. | 0.795 |
emrK | mdtA | b2368 | b2074 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system, subunit A; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.934 |
emrK | mdtG | b2368 | b1053 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Putative drug efflux system protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.641 |
emrK | mdtH | b2368 | b1065 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin. | 0.805 |
emrK | mdtK | b2368 | b1663 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system transporter; Multidrug efflux pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP). Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium. Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing [...] | 0.571 |
emrK | mdtL | b2368 | b3710 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system protein; Confers resistance to chloramphenicol. Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily. | 0.542 |
emrK | mdtM | b2368 | b4337 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Multidrug efflux system protein; Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP; Belongs to the major facilitator superfamily. | 0.634 |
emrK | mdtP | b2368 | b4080 | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. | Outer membrane factor of efflux pump; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride. | 0.883 |
fsr | mdtG | b0479 | b1053 | Putative fosmidomycin efflux system protein; Confers the resistance against fosmidomycin; Belongs to the major facilitator superfamily. | Putative drug efflux system protein; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. | 0.603 |
fsr | mdtH | b0479 | b1065 | Putative fosmidomycin efflux system protein; Confers the resistance against fosmidomycin; Belongs to the major facilitator superfamily. | Multidrug resistance protein MdtH; Confers resistance to norfloxacin and enoxacin. | 0.733 |
fsr | mdtK | b0479 | b1663 | Putative fosmidomycin efflux system protein; Confers the resistance against fosmidomycin; Belongs to the major facilitator superfamily. | Multidrug efflux system transporter; Multidrug efflux pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP). Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium. Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing [...] | 0.480 |