STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flgAAssembly protein for flagellar basal-body periplasmic p ring; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly (219 aa)    
Predicted Functional Partners:
flgB
Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
 
  
 0.998
flgD
Flagellar biosynthesis, initiation of hook assembly; Required for flagellar hook formation. May act as a scaffolding protein
 
  
 0.998
flgN
Flagellar biosynthesis protein flgn; Required for the efficient initiation of filament assembly
 
  
 0.995
flgJ
Flagellar rod assembly protein and murein hydrolase; Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space
 
  
 0.995
flgM
Negative regulator of flagellin synthesis flgm; Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA
 
  
 0.994
flgC
Flagellar component of cell-proximal portion of basal-body rod; Belongs to the flagella basal body rod proteins family
 
  
 0.994
flgH
Flagellar protein of basal-body outer-membrane l ring; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation
 
  
 0.993
flgE
Flagellar hook protein flge; Flagellar biosynthesis, hook protein; Protein involved in flagellum assembly and taxis
 
  
 0.992
flgG
Flagellar component of cell-distal portion of basal-body rod; Belongs to the flagella basal body rod proteins family
 
  
 0.992
flgF
Flagellar component of cell-proximal portion of basal-body rod; Belongs to the flagella basal body rod proteins family
 
  
 0.990
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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