STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potCSpermidine/putrescine transport system permease protein PotC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine (264 aa)    
Predicted Functional Partners:
potD
Spermidine/putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein
 
 0.999
potB
Spermidine/putrescine transport system permease protein PotB; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine
0.999
potA
Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family
 
 0.999
potH
Putrescine transport system permease protein PotH; Required for the activity of the bacterial periplasmic transport system of putrescine
 0.997
potG
Putrescine transport ATP-binding protein PotG; Part of the binding-protein-dependent transport system for putrescine. Probably responsible for energy coupling to the transport system
 
 0.971
kdpB
Potassium-transporting ATPase ATP-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
   
 
  0.946
malF
Maltose transport system permease protein MalF; Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane
     
 0.941
potF
Putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine. Polyamine binding protein
  
 0.939
ugpC
Sn-glycerol-3-phosphate import ATP-binding protein UgpC; Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
 
 0.929
malK
Maltose/maltodextrin import ATP-binding protein MalK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family
 
 0.924
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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