STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potBSpermidine/putrescine transport system permease protein PotB; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine (275 aa)    
Predicted Functional Partners:
potD
Spermidine/putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein
 
 0.999
potC
Spermidine/putrescine transport system permease protein PotC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine
0.999
potA
Spermidine/putrescine import ATP-binding protein PotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family
 0.999
potI
Putrescine transport system permease protein PotI; Required for the activity of the bacterial periplasmic transport system of putrescine
 0.996
ydcV
Inner membrane ABC transporter permease protein YdcV; Probably part of the binding-protein-dependent transport system YdcSTUV; probably responsible for the translocation of the substrate across the membrane
 
 0.974
potG
Putrescine transport ATP-binding protein PotG; Part of the binding-protein-dependent transport system for putrescine. Probably responsible for energy coupling to the transport system
 0.967
malF
Maltose transport system permease protein MalF; Part of the binding-protein-dependent transport system for maltose; probably responsible for the translocation of the substrate across the membrane
     
 0.928
ugpC
Sn-glycerol-3-phosphate import ATP-binding protein UgpC; Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters
 0.925
msbA
Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
   
 
  0.922
potH
Putrescine transport system permease protein PotH; Required for the activity of the bacterial periplasmic transport system of putrescine
  
  
0.917
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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