STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ymfDE14 prophage; putative SAM-dependent methyltransferase; Uncharacterized protein YmfD; Phage or Prophage Related (221 aa)    
Predicted Functional Partners:
ymfE
E14 prophage; uncharacterized protein YmfE; Uncharacterized protein YmfE; Phage or Prophage Related
  
  
 0.989
yafE
Putative s-adenosyl-l-methionine-dependent methyltransferase; Belongs to the methyltransferase superfamily
  
  
 0.822
yafS
annotation not available
  
  
 0.795
intE
E14 prophage; putative integrase; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome
   
  
 0.758
ycgX
Uncharacterized protein ycgx; To E.coli YbcV and YdfO
   
  
 0.740
ycgG
Putative membrane-anchored cyclic-di-gmp phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG
      
 0.735
stfR
Rac prophage; putative membrane protein; Prophage side tail fiber protein homolog StfR; Phage or Prophage Related; Belongs to the tail fiber family
   
  
 0.683
ygiQ
annotation not available
     
 0.656
ydaF
Uncharacterized protein YdaF; Phage or Prophage Related; To E.coli YdfA
      
 0.633
cmoB
Trna (cmo5u34)-carboxymethyltransferase, carboxy-sam-dependent; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. Can also catalyze the SAM-dependent methylation of ho5U, with much lower efficiency
  
  
 0.628
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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