STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ymfMUncharacterized protein YmfM; Phage or Prophage Related (112 aa)    
Predicted Functional Partners:
ymfL
Uncharacterized protein YmfL; Phage or Prophage Related
  
  
 0.990
kilR
Causes inhibition of cell division. At high levels of expression, can also abolish the rod shape of the cells. Division inhibition by KilR can be relieved by overexpression of the cell division protein FtsZ
      
 0.780
croE
Prophage transcriptional regulatory protein; Phage or Prophage Related
  
    0.779
ybhJ
Uncharacterized protein YbhJ; Putative enzyme
      
 0.737
yafW
Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI . It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism . Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells .
      
 0.734
dicB
Involved in cell division inhibition; this function can be repressed by DicA and DicC proteins as well as antitoxin CbeA (yeeU).
      
 0.731
ymfJ
Uncharacterized protein YmfJ; Phage or Prophage Related
  
    0.680
ykgO
annotation not available
      
 0.641
ykfI
Toxic component of a type IV toxin-antitoxin (TA) system . Acts as a toxin inhibitor that blocks cell division and cell elongation via FtsZ and possibly also MreB (although no interaction with MreB has been proven) . Overexpression results in inhibition of growth in liquid cultures and a decrease in colony formation (PubMed:14594833, PubMed:28257056, PubMed:28931012). These effects are overcome by concomitant expression of cognate antitoxin YafW, which leads to toxin loss by an unknown mechanism . Overexpression leads to formation of lemon-shaped cells and cell lysis; inactivated by ov [...]
      
 0.638
cohE
Prophage repressor CohE; Phage or Prophage Related
     
 0.609
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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