node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dcuA | dhaR | b4138 | b1201 | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | 0.781 |
dhaK | dhaL | b1200 | b1199 | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | 0.999 |
dhaK | dhaM | b1200 | b1198 | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | 0.999 |
dhaK | dhaR | b1200 | b1201 | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | 0.999 |
dhaK | ycgV | b1200 | b1202 | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | Putative autotransporter adhesin ycgv; Uncharacterized protein YcgV; Putative adhesion and penetration protein | 0.610 |
dhaL | dhaK | b1199 | b1200 | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | 0.999 |
dhaL | dhaM | b1199 | b1198 | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | 0.999 |
dhaL | dhaR | b1199 | b1201 | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | 0.999 |
dhaM | dhaK | b1198 | b1200 | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | 0.999 |
dhaM | dhaL | b1198 | b1199 | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | 0.999 |
dhaM | dhaR | b1198 | b1201 | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | 0.967 |
dhaM | rpoN | b1198 | b3202 | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | Rna polymerase, sigma 54 (sigma n) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC) | 0.598 |
dhaR | dcuA | b1201 | b4138 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Anaerobic c4-dicarboxylate transporter dcua; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane | 0.781 |
dhaR | dhaK | b1201 | b1200 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Dihydroxyacetone kinase, pts-dependent, dihydroxyacetone-binding subunit; Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP . Binds covalently dihydroxyacetone in hemiaminal linkage . DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL- ADP [...] | 0.999 |
dhaR | dhaL | b1201 | b1199 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Phosphoenolpyruvate---glycerone phosphotransferase subunit dhal; ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone . DhaL-ADP is converted to DhaL- ATP via a phosphoryl group transfer from DhaM and transmits it to dihydroxyacetone bound to DhaK . DhaL acts also as coactivator of the transcription activator DhaR by binding to the sensor domain of DhaR . In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity . In the absence of dihydroxyacetone, DhaL-A [...] | 0.999 |
dhaR | dhaM | b1201 | b1198 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Putative dihydroxyacetone-specific pts enzymes: hpr, ei components; Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone | 0.967 |
dhaR | puuC | b1201 | b1300 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Catalyzes the oxidation of 3-hydroxypropionaldehyde (3-HPA) to 3-hydroxypropionic acid (3-HP) . It acts preferentially with NAD but can also use NADP . 3-HPA appears to be the most suitable substrate for PuuC followed by isovaleraldehyde, propionaldehyde, butyraldehyde, and valeraldehyde . It might play a role in propionate and/or acetic acid metabolisms . Also involved in the breakdown of putrescine through the oxidation of gamma-Glu-gamma-aminobutyraldehyde to gamma-Glu-gamma-aminobutyrate (gamma-Glu-GABA) | 0.830 |
dhaR | rpoN | b1201 | b3202 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Rna polymerase, sigma 54 (sigma n) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of enzymes involved in arginine catabolism. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC) | 0.609 |
dhaR | ycgV | b1201 | b1202 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Putative autotransporter adhesin ycgv; Uncharacterized protein YcgV; Putative adhesion and penetration protein | 0.736 |
dhaR | yphE | b1201 | b2547 | Dna-binding transcriptional dual regulator dhar; Positively regulates the dhaKLM operon from a sigma-70 promoter. Represses its own expression | Putative abc transporter atp-binding protein yphe; Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system | 0.814 |