STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ychATransglutaminase-like TPR-repeat protein; Protein involved in regulation of transcription, DNA-dependent; Belongs to the UPF0162 family. (269 aa)    
Predicted Functional Partners:
ychQ
SIRB family inner membrane protein; Protein involved in regulation of transcription, DNA-dependent.
  
  
 0.983
prmC
RF-1 and RF-2 N5-glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif, i.e. on 'Gln-235' in RF1 and on 'Gln- 252' in RF2; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
  
    0.814
prfA
Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.813
yneE
Bestrophin family putative inner membrane protein.
      
 0.813
yobD
UPF0266 family inner membrane protein.
      
 0.736
yjhU
Uncharacterized transcriptional regulator YjhU; IS1 transposase B;IS, phage, Tn; Transposon-related functions; extrachromosomal; transposon related; Belongs to the SorC transcriptional regulatory family.
      
 0.732
kdsA
3-deoxy-D-manno-octulosonate 8-phosphate synthase; Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.
  
    0.729
ygfB
UPF0149 family protein; Belongs to the UPF0149 family.
  
    0.714
yihY
BrkB family putative transporter, inner membrane protein; tRNA processing exoribonuclease BN.
  
   
 0.714
hemA
Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). In the absence of NADPH, exhibits substrate esterase activity, leading to the release of glutamate from tRNA.
  
    0.702
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.