STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ychATransglutaminase-like/tpr repeat-containing protein; Belongs to the UPF0162 family (269 aa)    
Predicted Functional Partners:
ychQ
Sirb family inner membrane protein; Protein involved in regulation of transcription, DNA-dependent
  
  
 0.990
prfA
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
 
    0.900
prmC
RF-1 and RF-2 N5-glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif, i.e. on 'Gln-235' in RF1 and on 'Gln- 252' in RF2
       0.888
yobD
annotation not available
      
 0.829
yjhU
KpLE2 phage-like element; putative DNA-binding transcriptional regulator YjhU; Belongs to the SorC transcriptional regulatory family
      
 0.821
yneE
annotation not available
      
 0.819
ybbA
Putative abc transporter atp-binding protein ybba; Belongs to the ABC transporter superfamily
      
 0.816
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth
  
    0.814
hemA
Glutamyl-trna reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). In the absence of NADPH, exhibits substrate esterase activity, leading to the release of glutamate from tRNA
       0.789
yihY
Brkb family putative transporter, inner membrane protein; UPF0761 membrane protein YihY; tRNA processing exoribonuclease BN
      
 0.788
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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