STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ychEUPF0056 family inner membrane protein; UPF0056 membrane protein YhcE; Putative channel protein (215 aa)    
Predicted Functional Partners:
ydiK
annotation not available
      
 0.671
yqhA
annotation not available
   
  
 0.646
yoaE
Putative membrane protein/conserved protein; UPF0053 inner membrane protein YoaE; Putative transport protein
      
 0.549
yajR
Inner membrane transport protein YajR; Putative transport protein; Protein involved in response to drug
      
 0.531
ulaG
L-ascorbate 6-phosphate lactonase; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions. Also shows phosphodiesterase activity, hydrolyzing phosphodiester bond in the artificial chromogenic substrate bis-p-nitrophenyl phosphate (bis-pNPP)
      
 0.517
leuL
Leu operon leader peptide; Involved in control of the biosynthesis of leucine
      
 0.499
uup
Probably plays a role in ribosome assembly or function; overexpression suppresses cold-sensitive growth of a bipA deletion (Probable). May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA at Holliday junctions. May be involved in the correct segregation of nucleoids . Has ATPase activity, binds DNA non-sequence specifically; the presence of DNA does not change the ATPase activity . Mutations in this gene cause an increase in RecA-independent precise excision of transposons and insertion elements, and also red [...]
     
 0.492
alaA
Glutamate--pyruvate aminotransferase alaa; Involved in the biosynthesis of alanine
      
 0.482
ynfM
Mfs transporter, ynfm family, putative membrane transport protein; Inner membrane transport protein YnfM; Putative transport protein
      
 0.480
yhgN
annotation not available
  
   
0.455
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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