STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pspDPeripheral inner membrane phage-shock protein; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. (73 aa)    
Predicted Functional Partners:
pspB
Psp operon transcription co-activator; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspB is involved in transcription regulation; Belongs to the PspB family.
  
  
 0.999
pspC
Psp operon transcription co-activator; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspC is involved in transcription regulation; Belongs to the phageshock PspC family.
  
  
 0.999
pspA
Regulatory protein for phage-shock-protein operon; The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp- specific transcriptional activator PspF. Is also required for membrane integrity, efficient translocation and maintenance of the proton motive force. Belongs to the PspA/IM30 family.
  
  
 0.994
pspE
Thiosulfate:cyanide sulfurtransferase (rhodanese); The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspE catalyzes the sulfur-transfer reaction from thiosulfate to cyanide, to form sulfite and thiocyanate. Also able to use dithiol (dithiothreitol) as an alternate sulfur acceptor. Also possesses a very low mercaptopyruvate sulfurtransferase activity.
  
  
 0.874
pspF
Psp operon transcriptional activator; Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.
  
  
 0.868
pspG
Phage shock protein G; Effector of the phage shock response.
   
  
 0.800
ygaV
Tributyltin-inducible repressor of ygaVP; Functions as transcription repressor.
   
  
 0.530
pqiA
Paraquat-inducible, SoxRS-regulated inner membrane protein; Component of a transport pathway that contributes to membrane integrity; Belongs to the PqiA family.
      
 0.497
ycjX
DUF463 family protein, puatative P-loop NTPase; Putative EC 2.1 enzymes; To H.influenzae HI_1637.
  
  
 0.475
ycjF
UPF0283 family inner membrane protein.
  
  
 0.475
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.