node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
insH1-4 | ynaI | b1331 | b1330 | IS5 transposase and trans-activator. | Mechanosensitive channel protein, very small conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.729 |
insH1-4 | ynaJ | b1331 | b1332 | IS5 transposase and trans-activator. | DUF2534 family putative inner membrane protein. | 0.713 |
mscK | mscL | b0465 | b3291 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | 0.941 |
mscK | mscM | b0465 | b4159 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | 0.611 |
mscK | mscS | b0465 | b2924 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | 0.461 |
mscK | ybdG | b0465 | b0577 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks. | 0.961 |
mscK | ybiO | b0465 | b0808 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, intermediate conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.456 |
mscK | ynaI | b0465 | b1330 | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | Mechanosensitive channel protein, very small conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.412 |
mscL | mscK | b3291 | b0465 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | 0.941 |
mscL | mscM | b3291 | b4159 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | 0.903 |
mscL | mscS | b3291 | b2924 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | 0.972 |
mscL | ybdG | b3291 | b0577 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks. | 0.914 |
mscL | ybiO | b3291 | b0808 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, intermediate conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.909 |
mscL | ynaI | b3291 | b1330 | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | Mechanosensitive channel protein, very small conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.909 |
mscM | mscK | b4159 | b0465 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, intermediate conductance, K+ regulated; Mechanosensitive channel that opens in response to membrane tension and specific ionic conditions. Requires high concentrations of external K(+), NH(4)(+), Rb(+) or Cs(+) to gate. May participate in the regulation of osmotic pressure changes within the cell, although it does not appear to have a major role in osmolarity regulation. Forms an ion channel of 1.0 nanosiemens conductance. The channel can remain active for between 30 seconds and over 3 minutes; it does not desensitize upon extended pressure. Its activi [...] | 0.611 |
mscM | mscL | b4159 | b3291 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, high conductance; Mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Forms a nonselective ion channel with a conductance of about 4 nanosiemens. Participates in the regulation of osmotic pressure changes within the cell. Opens at a pressure just below that which would cause cell disruption and death. The force required to trigger channel opening depends on the membrane lipids composition. | 0.903 |
mscM | mscS | b4159 | b2924 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, small conductance; Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa. The channel is characterized by short bursts of activ [...] | 0.486 |
mscM | ybdG | b4159 | b0577 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel of miniconductance that confers protection against mild hypoosmotic shock. Overexpression confers protection against severe shocks. | 0.914 |
mscM | ybiO | b4159 | b0808 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, intermediate conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.916 |
mscM | ynaI | b4159 | b1330 | Mechanosensitive channel protein, miniconductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Gates spontaneously in response to increased membrane tension. | Mechanosensitive channel protein, very small conductance; Mechanosensitive channel that protects cells against hypoosmotic stress when highly overexpressed. Belongs to the MscS (TC 1.A.23) family. | 0.430 |