STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydaNZinc transport protein ZntB; Mediates efflux of zinc ions (327 aa)    
Predicted Functional Partners:
dcp
Dipeptidyl carboxypeptidase; Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides; Belongs to the peptidase M3 family
      
 0.809
loiP
Metalloprotease LoiP; Metalloprotease that cleaves substrates preferentially between Phe-Phe residues. Plays a role in response to some stress conditions. Seems to regulate the expression of speB
      
 0.809
dbpA
ATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. Requires a single-stranded RNA loading site on the 3' side of the substrate helix
      
 0.804
folE
GTP cyclohydrolase 1; Protein involved in folic acid biosynthetic process; Belongs to the GTP cyclohydrolase I family
     
 0.758
adhP
Alcohol dehydrogenase, propanol-preferring; Preferred specificity is towards 1-propanol; Belongs to the zinc-containing alcohol dehydrogenase family
     
 0.688
zupT
Zinc transporter ZupT; Mediates zinc uptake. May also transport other divalent cations such as copper and cadmium ions
     
 0.673
ydaM
Probable diguanylate cyclase YdaM; Part of a 2 protein system that seems to be dedicated to regulate transcription of csgD. The CsdG protein in turn regulates expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antagonized by the phosphodiesterase Gmr (YciR). In vitro has weak diguanylate cyclase activity. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria
  
    0.467
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
     
 0.435
znuA
High-affinity zinc uptake system protein ZnuA; Involved in the high-affinity zinc uptake transport system
      
 0.430
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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