|ydaC||DUF1187 family protein, Rac prophage; Helps to maintain the integrity of the chromosome by lowering the steady-state level of double strand breaks. This region of DNA acts as an antitoxin to toxin RalR, a DNase, but it seems to be sRNA RalA that has the antitoxin activity and not this putative protein. Therefore the identity of this as a protein-coding gene has been cast into doubt. (69 aa)|| |
Predicted Functional Partners:
Rac prophage; Putative lambdoid prophage Rac excisionase.
| || || || || ||0.971
Rac prophage; Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand. Has RAL-like activity.
| || || || || ||0.969
Killing protein, Rac prophage; Causes inhibition of cell division. At high levels of expression, can also abolish the rod shape of the cells. Division inhibition by KilR can be relieved by overexpression of the cell division protein FtsZ.
| || || || || ||0.958
| || || || || ||0.917
Rac prophage; Binds to single-stranded DNA and also promotes the renaturation of complementary single-stranded DNA. Function in recombination. Has a function similar to that of lambda RedB.
| || || || || ||0.798
Rac prophage; Is involved in the RecE pathway of recombination. Catalyzes the degradation of double-stranded DNA. Acts progressively in a 5' to 3' direction, releasing 5'-phosphomononucleotides. Has a strong preference for linear duplex substrate DNA and appears to be unable to initiate degradation from single-stranded breaks in DNA.
| || || || || ||0.778
Conserved protein, Rac prophage.
| || || || || || ||0.736
Rac prophage; uncharacterized protein.
| || || || || || ||0.673
Uncharacterized protein, Rac prophage; To E.coli YdfA.
| || || || || || || ||0.623
tRNA s(2)C32 thioltransferase, iron sulfur cluster protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. Belongs to the TtcA family.
| || || || || || ||0.591