STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hslJHeat-inducible lipoprotein involved in novobiocin resistance; Heat shock protein hslJ; Protein involved in response to temperature stimulus (140 aa)    
Predicted Functional Partners:
ldhA
Fermentative d-lactate dehydrogenase, nad-dependent; Fermentative lactate dehydrogenase
  
    0.762
yiaD
PF13488 family lipoprotein YiaD; Suppresses temperature-sensitive mutations in BamB when overexpressed
      
 0.604
uspC
Universal stress protein c; Required for resistance to DNA-damaging agents
  
     0.595
yjfY
annotation not available
  
     0.579
cysB
Lysr family transcriptional regulator, cys regulon transcriptional activator; This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription
      
 0.573
yegD
Hsp70 chaperone family protein; Belongs to the heat shock protein 70 family
 
   
 0.553
ppdA
Putative prepilin peptidase-dependent protein; Not yet known
  
     0.547
yhdV
annotation not available
  
     0.511
yaiW
annotation not available
   
  
 0.510
thiS
Immediate sulfur donor in thiazole formation; Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate
  
     0.488
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.