STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydcIPutative dna-binding transcriptional repressor ydci; Belongs to the LysR transcriptional regulatory family (307 aa)    
Predicted Functional Partners:
yeiI
Uncharacterized sugar kinase YeiI; Putative enzyme; Not classified; Belongs to the carbohydrate kinase PfkB family
      
 0.789
ybiH
Tetr/acrr family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons
  
   
 0.768
sdhC
Succinate dehydrogenase / fumarate reductase, cytochrome b subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH)
   
    0.743
yhjC
Putative dna-binding transcriptional regulator yhjc; Belongs to the LysR transcriptional regulatory family
  
  
 0.734
yjiR
Fused putative dna-binding transcriptional regulator/putative aminotransferase yjir; In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family
      
 0.732
sdhD
Succinate dehydrogenase / fumarate reductase, membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH)
   
    0.727
yddM
Putative dna-binding transcriptional regulator yddm; Belongs to the VapA/VapI family
      
 0.678
glcC
Gntr family transcriptional regulator, glc operon transcriptional activator; Transcriptional activator of the glcDEFGB operon which is associated with glycolate utilization, and encodes malate synthase G and the genes needed for glycolate oxidase activity Also negatively regulates the transcription of its own gene . Glycolate acts as an effector, but GlcC can also use acetate as an alternative effector
   
    0.640
yiaJ
Iclr family transcriptional regulator, carbohydrate utilization repressor; Negatively controls the transcription of the yiaKLMNOPQRS operon, which may be involved in the utilization of 2,3-diketo-L- gulonate
      
 0.616
yeiW
annotation not available
      
 0.612
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (3%) [HD]