node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
rlmN | ycjD | b2517 | b1289 | Dual specificity 23s rrna m(2)a2503, trna m(2)a37 methyltransferase, sam-dependent; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | 0.475 |
rlmN | ydcP | b2517 | b1435 | Dual specificity 23s rrna m(2)a2503, trna m(2)a37 methyltransferase, sam-dependent; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | 0.729 |
rlmN | ydiO | b2517 | b1695 | Dual specificity 23s rrna m(2)a2503, trna m(2)a37 methyltransferase, sam-dependent; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation | Putative acyl-coa dehydrogenase; Belongs to the acyl-CoA dehydrogenase family | 0.422 |
selB | ydcP | b3590 | b1435 | Selenocysteyl-trna-specific translation elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | 0.751 |
ybgD | ydcP | b0719 | b1435 | Putative fimbrial-like adhesin protein; Belongs to the fimbrial protein family | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | 0.737 |
ybgD | ygcN | b0719 | b2766 | Putative fimbrial-like adhesin protein; Belongs to the fimbrial protein family | Electron transfer flavoprotein-quinone oxidoreductase; Probably accepts electrons from YgcQ/YgcR and reduces a quinone | 0.876 |
ybgD | yhaB | b0719 | b3120 | Putative fimbrial-like adhesin protein; Belongs to the fimbrial protein family | annotation not available | 0.885 |
ycjD | rlmN | b1289 | b2517 | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | Dual specificity 23s rrna m(2)a2503, trna m(2)a37 methyltransferase, sam-dependent; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation | 0.475 |
ycjD | ydcN | b1289 | b1434 | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | Xre family transcriptional regulator, regulator of sulfur utilization; Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes | 0.731 |
ycjD | ydcP | b1289 | b1435 | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | 0.825 |
ycjD | ydcS | b1289 | b1440 | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | Putative abc transporter periplasmic binding protein/polyhydroxybutyrate synthase; Catalyzes the formation of short polymers of R-3- hydroxybutyrate (cPHB) . Involved in natural transformation . Probably part of the ABC transporter complex YdcSTUV. During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable) | 0.603 |
ycjD | ydiO | b1289 | b1695 | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | Putative acyl-coa dehydrogenase; Belongs to the acyl-CoA dehydrogenase family | 0.740 |
ydcN | ycjD | b1434 | b1289 | Xre family transcriptional regulator, regulator of sulfur utilization; Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | 0.731 |
ydcN | ydcP | b1434 | b1435 | Xre family transcriptional regulator, regulator of sulfur utilization; Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | 0.893 |
ydcN | ydcS | b1434 | b1440 | Xre family transcriptional regulator, regulator of sulfur utilization; Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes | Putative abc transporter periplasmic binding protein/polyhydroxybutyrate synthase; Catalyzes the formation of short polymers of R-3- hydroxybutyrate (cPHB) . Involved in natural transformation . Probably part of the ABC transporter complex YdcSTUV. During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable) | 0.501 |
ydcP | rlmN | b1435 | b2517 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | Dual specificity 23s rrna m(2)a2503, trna m(2)a37 methyltransferase, sam-dependent; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. Unmodified tRNA is not a suitable substrate for RlmN, which suggests that RlmN works in a late step during tRNA maturation | 0.729 |
ydcP | selB | b1435 | b3590 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | Selenocysteyl-trna-specific translation elongation factor; Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP | 0.751 |
ydcP | ybgD | b1435 | b0719 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | Putative fimbrial-like adhesin protein; Belongs to the fimbrial protein family | 0.737 |
ydcP | ycjD | b1435 | b1289 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925 | 0.825 |
ydcP | ydcN | b1435 | b1434 | Responsible for the formation of the 5-hydroxycytidine modification at the C2501 position (ho5C2501) of 23S rRNA. May be a Fe- S protein that catalyzes ho5C2501 formation using prephenate as a hydroxyl group donor | Xre family transcriptional regulator, regulator of sulfur utilization; Regulates the expression of 12-16 transcription units involved in various steps of sulfur utilization. Represses expression of pfkB, fliZ, cysE, ydcO and its own expression. Activates expression of ypfN. Acts by binding to SutR boxes | 0.893 |