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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yncJannotation not available (76 aa)    
Predicted Functional Partners:
yidZ
Putative lysr-type transcriptional regulator yidz; Involved in anaerobic NO protection
  
     0.687
wcaD
Putative colanic acid polymerase; Putative enzyme; Phage-related functions and prophages
  
   
 0.679
ydhZ
Uncharacterized protein; In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate
  
     0.676
mgrB
Regulatory peptide for phopq, feedback inhibition; Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. PhoP-regulated transcription is redox- sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway; the 2 periplasmic Cys residues of MgrB are required for its action on PhoQ, and thus PhoP
  
    0.623
wcaC
Putative colanic acid biosynthesis glycosyl transferase WcaC; Protein involved in colanic acid biosynthetic process
      
 0.620
wcaB
Putative colanic acid biosynthesis acetyltransferase wcab; Putative transferase; Protein involved in colanic acid biosynthetic process
      
 0.619
yqaE
annotation not available
      
 0.619
hofP
Dna utilization protein hofp; Required for the use of extracellular DNA as a nutrient
  
     0.616
ydcS
Putative abc transporter periplasmic binding protein/polyhydroxybutyrate synthase; Catalyzes the formation of short polymers of R-3- hydroxybutyrate (cPHB) . Involved in natural transformation . Probably part of the ABC transporter complex YdcSTUV. During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable)
     
 0.608
ynaJ
annotation not available
  
     0.605
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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