STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydcUPutative spermidine/putrescine transport system permease protein; Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane (313 aa)    
Predicted Functional Partners:
ydcS
Putative abc transporter periplasmic binding protein/polyhydroxybutyrate synthase; Catalyzes the formation of short polymers of R-3- hydroxybutyrate (cPHB) . Involved in natural transformation . Probably part of the ABC transporter complex YdcSTUV. During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable)
 
 
 0.998
ydcV
Putative spermidine/putrescine transport system permease protein; Involved in natural transformation . Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane. During natural transformation, may serve as the channel for dsDNA uptake (Probable)
 0.998
ydcT
Putative spermidine/putrescine transport system atp-binding protein; Probably part of the ABC transporter complex YdcSTUV. Probably responsible for energy coupling to the transport system
 0.996
patD
Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA) . This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal, which allows E.coli to grow on putrescine as the sole nitrogen source Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate . Can also oxidize n-alkyl medium-chain aldehydes, b [...]
 
    0.894
yfeS
annotation not available
      
 0.734
potI
Putrescine abc transporter membrane subunit poti; Required for the activity of the bacterial periplasmic transport system of putrescine
 
 0.730
yfeK
annotation not available
      
 0.679
potD
Spermidine preferential abc transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein
 
  
 0.636
yohC
annotation not available
   
  
 0.619
potF
Putrescine abc transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine. Polyamine binding protein
 
  
 0.612
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.