STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydcYannotation not available (77 aa)    
Predicted Functional Partners:
ydcX
Acts as an orphan toxin which is important for maintaining cell fitness during stress related to the stringent response (decreased amino acid, purine and thymidine availability). Overexpression inhibits cell growth and increases the formation of persister cells. Causes 99.9% of cells to undergo bacterial lysis within 2 hours after induction; nucleoids condense, the cytoplasm seems empty and the periplasmic space enlarges. The intracellular ATP level decreases about 27-fold suggesting the membrane potential may be disrupted.
 
   
 0.931
yciZ
annotation not available
  
   
 0.922
dsrB
annotation not available
      
 0.782
yjiM
Belongs to the FldB/FldC dehydratase alpha/beta subunit family
      
 0.782
ysaB
annotation not available
  
     0.782
yjbT
Belongs to the YjbT family
      
 0.781
ydcK
Uncharacterized acetyltransferase YdcK; Putative enzyme; Not classified; Belongs to the transferase hexapeptide repeat family
  
     0.780
yidG
annotation not available
  
     0.778
cedA
Activates the cell division inhibited by chromosomal DNA over-replication
  
     0.772
ydhZ
In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate
  
     0.767
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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