Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aat | elaA | b0885 | b2267 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | Belongs to the UPF0039 (ElaA) family | 0.570 |
| aat | mnaT | b0885 | b1448 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | 0.731 |
| aat | rimJ | b0885 | b1066 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | Acetylates the N-terminal alanine of ribosomal protein S5 . Also plays a role in maturation of the 30S ribosomal subunit . Plays a role in the temperature regulation of pap pilin transcription . ECO:0000269|PubMed:18466225, ECO:0000269|PubMed:20176963, | 0.427 |
| aat | yafP | b0885 | b0234 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | annotation not available | 0.422 |
| aat | yiaC | b0885 | b3550 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins. Overexpression inhibits motility. | 0.430 |
| aat | yjaB | b0885 | b4012 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins . Binds acetyl-CoA | 0.487 |
| aat | yjgM | b0885 | b4256 | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | Belongs to the acetyltransferase family | 0.591 |
| elaA | aat | b2267 | b0885 | Belongs to the UPF0039 (ElaA) family | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | 0.570 |
| elaA | mnaT | b2267 | b1448 | Belongs to the UPF0039 (ElaA) family | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | 0.830 |
| elaA | pka | b2267 | b2584 | Belongs to the UPF0039 (ElaA) family | Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II (PubMed:21981926, PubMed:22124017, PubMed:26847092). Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits . Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity . Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility . ECO:0000269|PubMed:220597 [...] | 0.712 |
| elaA | rimJ | b2267 | b1066 | Belongs to the UPF0039 (ElaA) family | Acetylates the N-terminal alanine of ribosomal protein S5 . Also plays a role in maturation of the 30S ribosomal subunit . Plays a role in the temperature regulation of pap pilin transcription . ECO:0000269|PubMed:18466225, ECO:0000269|PubMed:20176963, | 0.863 |
| elaA | yafP | b2267 | b0234 | Belongs to the UPF0039 (ElaA) family | annotation not available | 0.883 |
| elaA | yiaC | b2267 | b3550 | Belongs to the UPF0039 (ElaA) family | N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins. Overexpression inhibits motility. | 0.877 |
| elaA | yjaB | b2267 | b4012 | Belongs to the UPF0039 (ElaA) family | N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins . Binds acetyl-CoA | 0.878 |
| elaA | yjgM | b2267 | b4256 | Belongs to the UPF0039 (ElaA) family | Belongs to the acetyltransferase family | 0.890 |
| mnaT | aat | b1448 | b0885 | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine | 0.731 |
| mnaT | elaA | b1448 | b2267 | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | Belongs to the UPF0039 (ElaA) family | 0.830 |
| mnaT | nnr | b1448 | b4167 | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.941 |
| mnaT | pka | b1448 | b2584 | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II (PubMed:21981926, PubMed:22124017, PubMed:26847092). Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits . Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity . Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility . ECO:0000269|PubMed:220597 [...] | 0.653 |
| mnaT | rimJ | b1448 | b1066 | Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine . Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glutamate are very poor substrat [...] | Acetylates the N-terminal alanine of ribosomal protein S5 . Also plays a role in maturation of the 30S ribosomal subunit . Plays a role in the temperature regulation of pap pilin transcription . ECO:0000269|PubMed:18466225, ECO:0000269|PubMed:20176963, | 0.705 |
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