STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yncDPutative tonb-dependent outer membrane receptor; Probable receptor, TonB-dependent (700 aa)    
Predicted Functional Partners:
yncE
Atp-binding protein, periplasmic, function unknown; Uncharacterized protein YncE; Putative receptor
 
   
 0.867
fhuE
Outer-membrane receptor for ferric coprogen and ferric-rhodotorulic acid; Required for the uptake of Fe(3+) via coprogen, ferrioxamine B, and rhodotorulic acid
  
 
 
 0.662
fepD
Ferric enterobactin abc transporter membrane subunit febd; Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane
  
  
 0.632
ycgJ
annotation not available
      
 0.608
ybdN
annotation not available
      
 0.604
gcd
Quinoprotein glucose dehydrogenase; GDH is probably involved in energy conservation rather than in sugar metabolism
 
    0.582
yjcB
annotation not available
  
     0.526
msyB
Acidic protein that suppresses heat sensitivity of a secy mutant; Could participate in the normal pathway of protein export
  
    0.524
ygjH
tRNA-binding protein YgjH; Putative tRNA synthetase; Protein involved in tRNA aminoacylation for protein translation
      
 0.520
fepB
Ferric enterobactin abc transporter periplasmic binding protein; Binds ferrienterobactin; part of the binding-protein- dependent transport system for uptake of ferrienterobactin
  
   
 0.491
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.