STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yddBPutative tonb-dependent outer membrane receptor; To H.influenzae HI_1369 (790 aa)    
Predicted Functional Partners:
pqqL
Putative periplasmic m16 family zinc metalloendopeptidase; Putative zinc protease
 
  
 0.994
yddA
Vitamin b12/bleomycin/antimicrobial peptide transport system atp-binding/permease protein; Inner membrane ABC transporter ATP-binding protein YddA; Putative transport; Not classified
 
  
 0.988
ybaN
Inner membrane protein YbaN; Orf; Not classified
     
 0.831
ybiX
Fe(ii)-dependent oxygenase superfamily protein; PKHD-type hydroxylase YbiX; Putative enzyme
  
   
 0.783
yliF
Putative membrane-anchored diguanylate cyclase; Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules
  
   
 0.777
yihF
Uncharacterized protein yihf; To E.coli YdgA and H.influenzae HI_1236
  
     0.774
yegI
Protein kinase-related putative non-specific dna-binding protein; Probable serine/threonine kinase
  
     0.768
nanC
Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria (Probable). NanC proteins form high- conductance channels which are open at low membrane potentials and which have a weak anion selectivity
  
   
 0.763
fiu
Putative iron siderophore outer membrane transporter; Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M, H47 and E492
 
 
 0.755
ydiE
Hemin uptake protein hemp homolog; To Y.enterocolitica HemP
     
 0.751
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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