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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yddAVitamin b12/bleomycin/antimicrobial peptide transport system atp-binding/permease protein; Inner membrane ABC transporter ATP-binding protein YddA; Putative transport; Not classified (561 aa)    
Predicted Functional Partners:
yddB
Putative tonb-dependent outer membrane receptor; To H.influenzae HI_1369
 
  
 0.988
pqqL
Putative periplasmic m16 family zinc metalloendopeptidase; Putative zinc protease
 
  
 0.954
paaZ
Catalyzes the hydrolytic ring cleavage of 2-oxepin-2(3H)- ylideneacetyl-CoA (oxepin-CoA) via the open-chain aldehyde intermediate to yield 3-oxo-5,6-dehydrosuberyl-CoA. The enzyme consists of a C- terminal (R)-specific enoyl-CoA hydratase domain (formerly MaoC) that cleaves the ring and produces the highly reactive 3-oxo-5,6- dehydrosuberyl-CoA semialdehyde and an N-terminal NADP-dependent aldehyde dehydrogenase domain that oxidizes the aldehyde to 3-oxo-5,6- dehydrosuberyl-CoA. Can also use crotonyl-CoA as substrate
   
 0.871
ybaN
Inner membrane protein YbaN; Orf; Not classified
      
 0.824
ydiE
Hemin uptake protein hemp homolog; To Y.enterocolitica HemP
  
  
 0.779
ycaM
Inner membrane transporter YcaM; Putative transport; Not classified
   
 
 0.748
yqjH
Nadph-dependent ferric chelate reductase; Plays a role in iron homeostasis under excess nickel conditions
     
 0.734
ybiX
Fe(ii)-dependent oxygenase superfamily protein; PKHD-type hydroxylase YbiX; Putative enzyme
      
 0.732
ydhV
annotation not available
      
 0.710
adhE
Acetaldehyde dehydrogenase / alcohol dehydrogenase; This enzyme has three activities: ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction
   
 
  0.667
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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