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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
marCannotation not available (221 aa)    
Predicted Functional Partners:
yidL
Uncharacterized HTH-type transcriptional regulator YidL; Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription
      
 0.816
yijO
Uncharacterized HTH-type transcriptional regulator YijO; Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription
      
 0.786
envY
Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB
      
 0.730
yeaM
Putative dna-binding transcriptional regulator; Negatively regulates expression of the nimT operon and its own expression. Acts by binding to the nimR-nimT intergenic region
      
 0.641
mdtL
Mfs transporter, dha1 family, multidrug resistance protein; Confers resistance to chloramphenicol
      
 0.610
yfiF
Rna methyltransferase, trmh family; Uncharacterized tRNA/rRNA methyltransferase YfiF; Protein involved in RNA modification
      
 0.607
marR
Marr family transcriptional regulator, multiple antibiotic resistance protein marr; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site
  
  
 0.606
chbR
Arac family transcriptional regulator, dual regulator of chb operon; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon
      
 0.606
melR
Arac family transcriptional regulator, melibiose operon regulatory protein; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site
      
 0.602
eutR
Arac family transcriptional regulator, ethanolamine operon transcriptional activator; Activates the transcription of the eut operon. Also positively regulates its own transcription. Probably binds ethanolamine and vitamin B12 as effectors (By similarity)
      
 0.581
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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