node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
chbR | envY | b1735 | b0566 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | 0.497 |
chbR | marC | b1735 | b1529 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | UPF0056 family inner membrane protein. | 0.477 |
chbR | melR | b1735 | b4118 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Melibiose operon transcriptional regulator; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site. | 0.667 |
chbR | yidL | b1735 | b3680 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.679 |
chbR | ypdC | b1735 | b2382 | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.854 |
dapD | marC | b0166 | b1529 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Protein involved in lysine biosynthetic process via diaminopimelate; Belongs to the transferase hexapeptide repeat family. | UPF0056 family inner membrane protein. | 0.540 |
envY | chbR | b0566 | b1735 | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | 0.497 |
envY | marC | b0566 | b1529 | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | UPF0056 family inner membrane protein. | 0.504 |
envY | melR | b0566 | b4118 | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | Melibiose operon transcriptional regulator; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site. | 0.443 |
envY | yidL | b0566 | b3680 | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.635 |
envY | ypdC | b0566 | b2382 | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.604 |
marC | chbR | b1529 | b1735 | UPF0056 family inner membrane protein. | Repressor of chb operon for N,N'-diacetylchitobiose utilization; Dual-function repressor/activator of the chbBCARFG operon. In the absence of the inducing sugar chitobiose, together with NagC, represses the chbBCARFG operon for the uptake and metabolism of chitobiose. In association with Crp, and probably in the presence of chitobiose 6-phosphate, induces the transcription of the chbBCARFG operon. | 0.477 |
marC | dapD | b1529 | b0166 | UPF0056 family inner membrane protein. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Protein involved in lysine biosynthetic process via diaminopimelate; Belongs to the transferase hexapeptide repeat family. | 0.540 |
marC | envY | b1529 | b0566 | UPF0056 family inner membrane protein. | Porin thermoregulatory transcriptional activator; Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB. | 0.504 |
marC | marR | b1529 | b1530 | UPF0056 family inner membrane protein. | Transcriptional repressor of multiple antibiotic resistance; Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site. | 0.521 |
marC | melR | b1529 | b4118 | UPF0056 family inner membrane protein. | Melibiose operon transcriptional regulator; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site. | 0.456 |
marC | ydiU | b1529 | b1706 | UPF0056 family inner membrane protein. | UPF0061 family protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr and Tyr residues of target proteins (AMPylation). Cannot use GTP, CTP or UTP as cosubstrate. AMPylates SucA at 'Thr-405' and GrxA on 'Tyr-13'. Regulates protein S-glutathionylation levels probably by AMPylation of deglutathionylation enzymes such as GrxA. Probably involved in redox homeostasis. | 0.529 |
marC | yfeX | b1529 | b2431 | UPF0056 family inner membrane protein. | Porphyrinogen oxidase, cytoplasmic; Has both general peroxidase activity and dye-decolorizing activity. Can catalyze the oxidation of both protoporphyrinogen IX and coproporphyrinogen III to their corresponding porphyrins. Also efficiently decolorizes the dyes alizarin red and Cibacron blue F3GA. | 0.520 |
marC | yfiF | b1529 | b2581 | UPF0056 family inner membrane protein. | Putative methyltransferase; Protein involved in RNA modification. | 0.506 |
marC | yidL | b1529 | b3680 | UPF0056 family inner membrane protein. | Putative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. | 0.680 |