Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
query proteins and first shell of interactors
second shell of interactors
proteins of unknown 3D structure
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
|ydfI||Belongs to the mannitol dehydrogenase family. UxuB subfamily (486 aa)|| |
Predicted Functional Partners:
Catalyzes the dehydration of D-mannonate.
| || || ||0.694
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family
| || || ||0.635
Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
| || || || || ||0.598
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.
| || || || || ||0.545
Probably involved in the degradation of homoserine lactone (HSL) or of a metabolite of HSL that signals starvation
| || || || || || ||0.527
In vitro catalyzes the addition of water to fumarate, forming malate. Cannot catalyze the reverse reaction. Cannot use the cis-isomer maleate as substrate
| || || || || || ||0.519
Catalyzes nitrate uptake, nitrite uptake and nitrite export across the cytoplasmic membrane. May function as a nitrate/H(+) and nitrite/H(+) channel. Could confer a selective advantage during severe nutrient starvation or slow growth. ECO:0000269|PubMed:15667293, ECO:0000269|PubMed:16804183,
| || || || || || ||0.513
Repressor of the rspAB operon. Acts by binding directly to the upstream region of rspA
| || || ||0.506
Probable electron transporter required for biotin synthase activity
| || || || || || || ||0.485
Uncharacterized protein YjiL; Putative enzyme
| || || || || || || ||0.483
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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