STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydfAUncharacterized protein YdfA; Phage or Prophage Related; To E.coli YdaF (51 aa)    
Predicted Functional Partners:
ydfB
Uncharacterized protein YdfB; Phage or Prophage Related
  
  
 0.982
ydfC
Uncharacterized protein YdfC; Phage or Prophage Related
  
  
 0.968
dicC
This protein is a repressor of division inhibition gene dicB
     
 0.885
dicA
This protein is a repressor of division inhibition gene dicB
     
 0.885
ydfD
Uncharacterized protein YdfD; Phage or Prophage Related
      
 0.875
dicB
Involved in cell division inhibition; this function can be repressed by DicA and DicC proteins as well as antitoxin CbeA (yeeU).
      
 0.822
nikB
Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane
      
 0.822
yfjP
To E.coli YkfA and YeeP
      
 0.731
ydfO
Uncharacterized protein YdfO; Phage or Prophage Related; To E.coli YbcV and YcgX
      
 0.672
topB
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in t [...]
      
 0.603
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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