| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asmA | bamC | b2064 | b2477 | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | 0.742 |
| asmA | ftsN | b2064 | b3933 | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | 0.555 |
| asmA | ydgA | b2064 | b1614 | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | annotation not available | 0.659 |
| asmA | yrfF | b2064 | b3398 | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | Inner membrane protein - inhibits the rcs signaling pathway; Putative membrane protein IgaA homolog; Putative dehydrogenase | 0.613 |
| bamC | asmA | b2477 | b2064 | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | 0.742 |
| bamC | ftsN | b2477 | b3933 | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | 0.767 |
| bamC | ydgA | b2477 | b1614 | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | annotation not available | 0.609 |
| bamC | yrfF | b2477 | b3398 | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | Inner membrane protein - inhibits the rcs signaling pathway; Putative membrane protein IgaA homolog; Putative dehydrogenase | 0.470 |
| frdA | ydgA | b4154 | b1614 | Anaerobic fumarate reductase catalytic and nad/flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth | annotation not available | 0.633 |
| ftsN | asmA | b3933 | b2064 | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | 0.555 |
| ftsN | bamC | b3933 | b2477 | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | 0.767 |
| ftsN | ydgA | b3933 | b1614 | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | annotation not available | 0.616 |
| ftsN | yrfF | b3933 | b3398 | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | Inner membrane protein - inhibits the rcs signaling pathway; Putative membrane protein IgaA homolog; Putative dehydrogenase | 0.545 |
| uidC | ydgA | b1615 | b1614 | Putative outer membrane porin for beta-glucuronides porin protein; Enhances the activity of the UidB (GusB) glucuronide transporter, on its own however it has no transport activity. Glucuronide transport does not occur in strain K12 due to a variant at position 100 of the UidB (GusB, AC P0CE44, AC P0CE45) protein | annotation not available | 0.671 |
| ydgA | asmA | b1614 | b2064 | annotation not available | Suppressor of ompf assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins | 0.659 |
| ydgA | bamC | b1614 | b2477 | annotation not available | Outer membrane protein assembly factor bamc; Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly [...] | 0.609 |
| ydgA | frdA | b1614 | b4154 | annotation not available | Anaerobic fumarate reductase catalytic and nad/flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth | 0.633 |
| ydgA | ftsN | b1614 | b3933 | annotation not available | Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases (Probable) . Required for full FtsI activity . Required for recruitment of AmiC to the septal ring | 0.616 |
| ydgA | uidC | b1614 | b1615 | annotation not available | Putative outer membrane porin for beta-glucuronides porin protein; Enhances the activity of the UidB (GusB) glucuronide transporter, on its own however it has no transport activity. Glucuronide transport does not occur in strain K12 due to a variant at position 100 of the UidB (GusB, AC P0CE44, AC P0CE45) protein | 0.671 |
| ydgA | yehA | b1614 | b2108 | annotation not available | Putative fimbrial-like adhesin protein; Part of the yehABCD fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches | 0.610 |
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