STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uidRTetr/acrr family transcriptional regulator, repressor for uid operon; Repressor for the uidRABC (gusRABC) operon (196 aa)    
Predicted Functional Partners:
uidA
Beta-d-glucuronidase; Belongs to the glycosyl hydrolase 2 family
 
   
 0.936
uxuR
Gntr family transcriptional regulator, uxu operon transcriptional repressor; Repressor for the uxuRBA operon
  
   
 0.904
lgoR
Gntr family transcriptional regulator, transcriptional activator for l-galactonate catabolism; May be a positive transcriptional regulator for lgoD and/or lgoT. Is essential for growth on L-galactonate as the sole carbon source
      
 0.788
malI
Laci family transcriptional regulator, maltose regulon regulatory protein; Repressor for the malX and malY genes. Also regulates its own expression. Binds maltose as an inducer
     
 0.772
exuR
Gntr family transcriptional regulator, hexuronate regulon transcriptional repressor; Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the ExuT, UxaCA and UxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers
      
 0.703
yddB
Putative tonb-dependent outer membrane receptor; To H.influenzae HI_1369
  
     0.629
yegI
Protein kinase-related putative non-specific dna-binding protein; Probable serine/threonine kinase
  
     0.621
bdcR
Tetr/acrr family transcriptional regulator, repressor for divergent bdca; Negatively regulates expression of bdcA
  
   
 0.618
hdhA
7-alpha-hydroxysteroid dehydrogenase, NAD-dependent; Catalyzes the oxidation of the 7-alpha-hydroxy group of primary bile acids such as cholate, chenodeoxycholate and taurochenodeoxycholate . To a lesser extent, also able to use taurocholate and glycocholate
     
 0.602
ycjW
Uncharacterized HTH-type transcriptional regulator YcjW; Putative LACI-type transcriptional regulator; Protein involved in transcription repressor activity and transcription
  
   
 0.578
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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