STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malIRepressor for the malX and malY genes. Also regulates its own expression. Binds maltose as an inducer (342 aa)    
Predicted Functional Partners:
malY
Acts as a beta-cystathionase and as a repressor of the maltose regulon
 
   
 0.857
hdhA
Catalyzes the oxidation of the 7-alpha-hydroxy group of primary bile acids such as cholate, chenodeoxycholate and taurochenodeoxycholate . To a lesser extent, also able to use taurocholate and glycocholate
   
 
 0.829
uidR
Repressor for the uidRABC (gusRABC) operon
     
 0.772
ebgR
Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer
  
     0.728
ytfQ
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Binds to both alpha- and beta- galactofuranose
    
 
 0.695
rsxG
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR .
      
 0.679
rsxD
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR .
      
 0.672
ybjX
To H.influenzae HI_0461
      
 0.641
dcp
Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides.
      
 0.641
ydeN
Belongs to the sulfatase family
      
 0.640
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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