STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydgJPutative oxidoreductase. (346 aa)    
Predicted Functional Partners:
cobB
Deacetylase of acs and cheY, chemotaxis regulator; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Activates the enzyme acetyl-CoA synthetase by deacetylating 'Lys-609' in the inactive, acetylated form of the enzyme. May also modulate the activity of other propionyl-adenosine monophosphate (AMP)-forming enzymes. Belongs to the sirtuin family. Class III subfamily.
    
   0.843
yceM
Putative virulence factor; Belongs to the Gfo/Idh/MocA family.
  
   
 0.716
ygfF
Putative oxidoreductase.
  
  
 0.712
ygjR
Putative NAD(P)-dependent dehydrogenase; Belongs to the Gfo/Idh/MocA family.
  
  
 0.703
blr
Beta-lactam resistance membrane protein; Component of the cell division machinery, which is probably involved in the stabilization of the divisome under certain stress conditions.
     
 0.700
yjhC
GFO/IDH/MOCA family putative oxidoreductase. NAD(P)-dependent; Putative dehydrogenase; Belongs to the Gfo/Idh/MocA family.
  
   
 0.688
ydjJ
Putative oxidoreductase.
   
  
 0.636
yggP
Putative Zn-binding dehydrogenase; To K.pneumoniae SorE.
   
  
 0.636
yohF
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.634
yhiN
Putative oxidoreductase; To H.influenzae HI_0933.
      
 0.622
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.