STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhKPutative efflux protein (PET) component of YdhJK efflux pump. (670 aa)    
Predicted Functional Partners:
ydhJ
Putative membrane fusion protein (MFP) of YdhJK efflux pump; Putative membrane protein.
  
 0.997
ydhI
DUF1656 family putative inner membrane efflux pump associated protein.
  
  
 0.963
yfeS
WGR domain protein.
      
 0.789
yfeK
Uncharacterized protein.
      
 0.734
yhfK
Putative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process.
  
     0.657
agp
Glucose-1-phosphatase/inositol phosphatase; Absolutely required for the growth of E.coli in a high- phosphate medium containing G-1-P as the sole carbon source; Belongs to the histidine acid phosphatase family.
  
     0.651
yaiW
Microcin Bac7 uptake protein; outer membrane surface-exposed lipoprotein.
      
 0.633
yidR
DUF3748 family protein.
      
 0.620
ypfG
DUF1176 family protein.
  
     0.606
slyA
Global transcriptional regulator; Transcription regulator that can specifically activate or repress expression of target genes. Activates expression of genes such as molecular chaperones (groL, groS, dnaK, grpE, and cbpA), proteins involved in acid resistance (hdeA, hdeB, and gadA), the starvation lipoprotein slp, virulence protein hlyE/clyA. Represses expression of genes involved in the histidine biosynthetic pathway such as hisA, hisB, hisD, hisF and hisG. Required for the activation of virulence genes; Belongs to the SlyA family.
     
 0.596
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.