STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhPInner membrane transport protein YdhP; Putative transport protein (389 aa)    
Predicted Functional Partners:
ynhF
annotation not available
     
 0.926
wcaI
Putative colanic biosynthesis glycosyl transferase; Protein involved in colanic acid biosynthetic process
    
 
 0.762
mlaC
Probable phospholipid-binding protein MlaC; Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the periplasmic space and deliver it to the MlaFEDB complex at the inner membrane
      
 0.751
wcaF
Putative transferase; Protein involved in colanic acid biosynthetic process
      
 0.750
wcaA
Putative colanic acid biosynthesis glycosyl transferase WcaA; Putative regulator; Protein involved in colanic acid biosynthetic process
   
 
 0.712
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily
   
  
 0.685
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits); In the N-terminal section; belongs to the glycosyltransferase 51 family
      
 0.680
cpsB
Mannose-1-phosphate guanylyltransferase; Involved in the biosynthesis of the capsular polysaccharide colanic acid
      
 0.680
kdpF
Potassium-transporting ATPase KdpF subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit may be involved in stabilization of the complex
      
 0.680
manA
Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide
    
 
 0.614
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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