STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhCPutative arabinose efflux transporter; Inner membrane transport protein YdhC; Putative transport protein (403 aa)    
Predicted Functional Partners:
ydhB
Putative lysr family dna-binding transcriptional regulator ydhb; Belongs to the LysR transcriptional regulatory family
 
 
 0.988
ydeE
Putative transporter; A transporter able to export peptides. When overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth . Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide
  
  
 0.804
yfcJ
Putative arabinose efflux transporter; Overexpression has no effect on intracellular arabinose concentrations
   
  
 0.795
yhhS
Putative arabinose efflux transporter; Confers high-level resistance to glyphosate when overexpressed . Overexpression has no effect on intracellular arabinose concentrations
    
 
 0.746
cfa
Cyclopropane fatty acyl phospholipid synthase, sam-dependent; Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge
      0.677
aaeA
Aromatic carboxylic acid efflux pump membrane fusion protein; Forms an efflux pump with AaeB
   
  
 0.647
mhpT
Mfs transporter, aahs family, 3-hydroxyphenylpropionic acid transporter; Uptake of 3-(3-hydroxyphenyl)propionate (3HPP) across the cytoplasmic membrane. Transport is driven by the proton motive force. Does not transport benzoate, 3-hydroxybenzoate or gentisate
      
 0.628
eamA
Cysteine and o-acetyl-l-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites
   
  
 0.528
setC
Mfs transporter, set family, sugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs
      
 0.514
mdtK
Multidrug resistance protein, mate family; Multidrug efflux pump that probably functions as a Na(+)/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin) and tetraphenylphosphonium ion (TPP) . Also to deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, ethidium bromide and benzalkonium . Also able to export peptides; when overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth . Cells overex [...]
      
 0.486
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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