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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhRPutative monooxygenase ydhr; May function as monooxygenase and play a role in the metabolism of aromatic compounds (101 aa)    
Predicted Functional Partners:
ygiN
Putative quinol monooxygenase ygin; Can oxidize menadiol to menadione
      
 0.877
ydhY
Putative 4fe-4s ferredoxin-type protein; Uncharacterized ferredoxin-like protein YdhY; Putative oxidoreductase, Fe-S subunit
      
 0.740
ydjY
annotation not available
      
 0.609
ydiH
annotation not available
  
  
 0.590
cnu
Nucleoid-associated oric-binding protein; Modifies the set of genes regulated by H-NS; Hha and Cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA . The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC . Can complement, at least partially, the absence of the Hha protein in hha mutants
      
 0.571
chrR
Chromate reductase, nad(p)h dehydrogenase (quinone); Catalyzes the reduction of quinones . Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2). Quinone reduction is probably the primary biological role of ChrR (By similarity). Can also reduce toxic chromate to insoluble and less toxic Cr(3+). Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount [...]
      
 0.561
ydhS
Uncharacterized protein YdhS; Putative enzyme; Not classified
       0.536
ycjD
DUF559 family endonuclease-related protein; To H.influenzae HI_1162 and to HI_0925
      
 0.520
wrbA
Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH
      
 0.476
yeaQ
annotation not available
      
 0.473
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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