STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydhSUncharacterized protein YdhS; Putative enzyme; Not classified (534 aa)    
Predicted Functional Partners:
ydaE
Rac prophage; zinc-binding protein; Uncharacterized protein YdaE; Phage or Prophage Related
      
 0.824
yeaX
Putative yeawx dioxygenase beta subunit, reductase component; Converts carnitine to trimethylamine and malic semialdehyde. Can also use gamma-butyrobetaine, choline and betaine as substrates
      
 0.813
yjdP
Uncharacterized protein YjdP; Conserved hypothetical protein; conserved in EDL933 and CFT073; on opposite strand of the now deaccessioned phnQ (b4091)
  
     0.721
ariR
Probable rcsb/c two-component-system connector, global regulator of biofilm formation and acid-resistance; Probably a connector protein for RcsB/C regulation of biofilm and acid-resistance, providing additional signal input into the two- component signaling pathway. May serve to stimulate biofilm maturation, via the Rcs phosphorelay. Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB/C two- component system. May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition. Also confers resi [...]
  
     0.709
ynjC
Putative thiamine transport system permease protein; Probably part of the binding-protein-dependent transport system YnjCD. Probably responsible for the translocation of the substrate across the membrane
  
     0.673
ydiE
Hemin uptake protein hemp homolog; To Y.enterocolitica HemP
  
     0.650
yeeE
UPF0394 inner membrane protein YeeE; Putative transport system permease protein
      
 0.640
ycgZ
Probably a connector protein for RcsB/C regulation of biofilm formation, providing additional signal input into the two-component signaling pathway. Partially antagonizes the activities of YmgA and AriR, proteins that, via the Rcs phosphorelay, promote the synthesis of colanic acid, an exopolysaccharide and matrix component
  
     0.631
ecpB
Mat/ecp fimbriae periplasmic chaperone; Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
  
     0.589
ecpE
Mat/ecp fimbriae periplasmic chaperone; Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity)
  
     0.578
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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