node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
btuE | nlpC | b1710 | b1708 | Glutathione peroxidase; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. In vitro, utilizes preferentially thioredoxin A to decompose hydrogen peroxide as well as cumene-, tert- butyl-, and linoleic acid hydroperoxides, suggesting that it may have one or more organic hydroperoxide as its physiological substrate. Belongs to the glutathione peroxidase family. BtuE subfamily. | Putative C40 clan peptidase lipoprotein; Lipoprotein. | 0.575 |
mepM | nlpC | b1856 | b1708 | Murein DD-endopeptidase, space-maker hydrolase, septation protein; A murein DD-endopeptidase with specificity for D-Ala-meso- diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. | Putative C40 clan peptidase lipoprotein; Lipoprotein. | 0.753 |
mepM | nlpD | b1856 | b2742 | Murein DD-endopeptidase, space-maker hydrolase, septation protein; A murein DD-endopeptidase with specificity for D-Ala-meso- diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | 0.596 |
mepM | slt | b1856 | b4392 | Murein DD-endopeptidase, space-maker hydrolase, septation protein; A murein DD-endopeptidase with specificity for D-Ala-meso- diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.775 |
mltB | nlpC | b2701 | b1708 | Membrane-bound lytic murein transglycosylase B; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Putative C40 clan peptidase lipoprotein; Lipoprotein. | 0.621 |
mltB | nlpD | b2701 | b2742 | Membrane-bound lytic murein transglycosylase B; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | 0.496 |
mltB | slt | b2701 | b4392 | Membrane-bound lytic murein transglycosylase B; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.922 |
nlpC | btuE | b1708 | b1710 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Glutathione peroxidase; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. In vitro, utilizes preferentially thioredoxin A to decompose hydrogen peroxide as well as cumene-, tert- butyl-, and linoleic acid hydroperoxides, suggesting that it may have one or more organic hydroperoxide as its physiological substrate. Belongs to the glutathione peroxidase family. BtuE subfamily. | 0.575 |
nlpC | mepM | b1708 | b1856 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Murein DD-endopeptidase, space-maker hydrolase, septation protein; A murein DD-endopeptidase with specificity for D-Ala-meso- diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. | 0.753 |
nlpC | mltB | b1708 | b2701 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Membrane-bound lytic murein transglycosylase B; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.621 |
nlpC | nlpD | b1708 | b2742 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | 0.594 |
nlpC | rrrD | b1708 | b0555 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | DLP12 prophage; Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity. Exhibits lytic activity against E.coli and S.typhi cell wall substrate; Belongs to the glycosyl hydrolase 24 family. | 0.594 |
nlpC | rrrQ | b1708 | b1554 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Qin prophage; Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity; Belongs to the glycosyl hydrolase 24 family. | 0.577 |
nlpC | slt | b1708 | b4392 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Lytic murein transglycosylase, soluble; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.614 |
nlpC | yaeF | b1708 | b0193 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Putative lipoprotein. | 0.893 |
nlpC | ydiV | b1708 | b1707 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | anti-FlhD4C2 factor, inactive EAL family phosphodiesterase; Upon overexpression acts as a novel anti-FlhC(2)FlhD(4) factor, decreasing its DNA-binding activity, able to negatively regulate expression of flagellar class II operons including FliC. | 0.570 |
nlpC | yiiX | b1708 | b3937 | Putative C40 clan peptidase lipoprotein; Lipoprotein. | Putative lipid binding hydrolase, DUF830 family protein; To E.coli YebB. | 0.730 |
nlpD | mepM | b2742 | b1856 | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | Murein DD-endopeptidase, space-maker hydrolase, septation protein; A murein DD-endopeptidase with specificity for D-Ala-meso- diaminopimelic acid (mDAP) cross-links. Its role is probably to cleave D-Ala-mDAP cross-links to allow insertion of new glycans and thus cell wall expansion. Functionally redundant with MepM and MepH. Partially suppresses an mepS disruption mutant. | 0.596 |
nlpD | mltB | b2742 | b2701 | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | Membrane-bound lytic murein transglycosylase B; Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.496 |
nlpD | nlpC | b2742 | b1708 | Activator of AmiC murein hydrolase activity, lipoprotein; Activator of the cell wall hydrolase AmiC. Required for septal murein cleavage and daughter cell separation during cell division. | Putative C40 clan peptidase lipoprotein; Lipoprotein. | 0.594 |