close STRING Database User Survey
Please help us improve further — take a moment to fill our brief user survey.
 
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydjNCystine/sulfocysteine:cation symporter; Involved in L-cystine transport. Can probably also transport L-cysteine. Mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys) (463 aa)    
Predicted Functional Partners:
yeeE
UPF0394 inner membrane protein YeeE; Putative transport system permease protein
   
  
 0.913
yeeD
annotation not available
   
  
 0.853
cysJ
Sulfite reductase (nadph) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component
   
  
 0.838
ydjM
Putative inner membrane protein regulated by lexa; To B.subtilis YvsG
     
 0.765
yeiB
DUF418 family putative inner membrane protein; Involved in transport
      
 0.734
yecS
Abc family putative inner membrane permease; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys) . Probably responsible for the translocation of the substrate across the membrane (Probable)
   
  
 0.729
cysP
Thiosulfate/sulfate abc transporter periplasmic binding protein cysp; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
   
    0.728
cysD
Sulfate adenylyltransferase subunit 2; Belongs to the PAPS reductase family. CysD subfamily
   
  
 0.726
qorB
Nad(p)h dehydrogenase (quinone); Quinone oxidoreductase that may play some additional role beyond quinone reduction. Potential redox sensor protein. Overexpression induces retardation of growth
      
 0.705
fliY
L-cystine transport system substrate-binding protein; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Binds cystine
   
  
 0.676
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
Server load: low (8%) [HD]