STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osmEOsmotically-inducible putative lipoprotein OsmE; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress (112 aa)    
Predicted Functional Partners:
dcrB
Periplasmic bacteriophage sensitivity protein dcrb; Required for phage C1 adsorption
  
 
 
 0.909
osmY
Salt-inducible putative abc transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress
   
 
 0.901
osmC
Lipoyl-dependent cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide
   
  
 0.868
wrbA
Nad(p)h dehydrogenase (quinone); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH
   
  
 0.860
msyB
Acidic protein that suppresses heat sensitivity of a secy mutant; Could participate in the normal pathway of protein export
  
    0.857
elaB
Putative membrane-anchored duf883 family ribosome-binding protein; Belongs to the ElaB/YgaM/YqjD family
   
  
 0.806
yccJ
annotation not available
  
    0.804
sra
Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein
   
  
 0.803
yqjD
Ribosome- and membrane-associated duf883 domain-containing protein yqjd; Upon overexpression inhibits growth
   
  
 0.794
yodD
annotation not available
  
  
 0.762
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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