STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydjEInner membrane metabolite transport protein YdjE; Putative transport protein (452 aa)    
Predicted Functional Partners:
ycjT
In vitro catalyzes the phosphorolysis of D-kojibiose into beta-D-glucose 1-phosphate and D-glucose. No other disaccharides tested substitute for D-kojibiose. In the reverse direction disaccharides can be formed from beta-D-glucose 1-phosphate plus D-glucose, L-sorbose, D- sorbitol, L-iditol or 1,5-anhydro-D-glucitol, but with low efficiency. The beta-D-glucose 1-phosphate product is the substrate for YcjU (AC P77366), the next apparent enzyme in the putative biochemical pathway encoded in this locus (yjcM to ycjW)
      
 0.877
ydjH
Uncharacterized sugar kinase YdjH; Putative enzyme; Not classified; Belongs to the carbohydrate kinase PfkB family
 
    0.783
emrY
Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs
    
 
 0.747
ydjG
Catalyzes the NADH-dependent reduction of methylglyoxal (2- oxopropanal) in vitro . It is not known if this activity has physiological significance . Cannot use NADPH as a cosubstrate . Seems to play some role in intestinal colonization .
 
    0.738
ydjL
Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjL; Putative enzyme; Not classified
 
 
   0.716
betB
Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. It is highly specific for betaine and has a significantly higher affinity for NAD than for NADP.
   
 
 0.709
ydjJ
Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ; Putative oxidoreductase
 
   0.706
grxB
Involved in reducing some disulfide bonds in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase
  
   
 0.694
ydjF
Uncharacterized HTH-type transcriptional regulator YdjF; Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent
 
     0.632
ydjI
Uncharacterized protein YdjI; Putative enzyme; Not classified
 
   0.604
Your Current Organism:
Escherichia coli K12 MG1655
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli K12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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