node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gldA | mgsA | b3945 | b0963 | Glycerol dehydrogenase, NAD+ dependent; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. In E.coli, an important role of GldA is also likely to regulate the intracellular level of dihydroxyacetone by catalyzing the reverse reaction, i.e. the conversion of dihydroxyacetone into glycerol. Possesses a broad substrate specificity, since it is also able to oxidize 1,2-propanediol and to reduce glycolaldehyde, methylglyoxal and hydroxyacetone into ethylene glycol, lac [...] | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.990 |
gldA | ydjG | b3945 | b1771 | Glycerol dehydrogenase, NAD+ dependent; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. In E.coli, an important role of GldA is also likely to regulate the intracellular level of dihydroxyacetone by catalyzing the reverse reaction, i.e. the conversion of dihydroxyacetone into glycerol. Possesses a broad substrate specificity, since it is also able to oxidize 1,2-propanediol and to reduce glycolaldehyde, methylglyoxal and hydroxyacetone into ethylene glycol, lac [...] | Methylglyoxal reductase, NADH-dependent; Catalyzes the NADH-dependent reduction of methylglyoxal (2- oxopropanal) in vitro. It is not known if this activity has physiological significance. Cannot use NADPH as a cosubstrate. Seems to play some role in intestinal colonization. | 0.930 |
gldA | yqhD | b3945 | b3011 | Glycerol dehydrogenase, NAD+ dependent; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. In E.coli, an important role of GldA is also likely to regulate the intracellular level of dihydroxyacetone by catalyzing the reverse reaction, i.e. the conversion of dihydroxyacetone into glycerol. Possesses a broad substrate specificity, since it is also able to oxidize 1,2-propanediol and to reduce glycolaldehyde, methylglyoxal and hydroxyacetone into ethylene glycol, lac [...] | Aldehyde reductase, NADPH-dependent; NADP-dependent ADH activity; Belongs to the iron-containing alcohol dehydrogenase family. | 0.979 |
mgsA | gldA | b0963 | b3945 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Glycerol dehydrogenase, NAD+ dependent; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. In E.coli, an important role of GldA is also likely to regulate the intracellular level of dihydroxyacetone by catalyzing the reverse reaction, i.e. the conversion of dihydroxyacetone into glycerol. Possesses a broad substrate specificity, since it is also able to oxidize 1,2-propanediol and to reduce glycolaldehyde, methylglyoxal and hydroxyacetone into ethylene glycol, lac [...] | 0.990 |
mgsA | ydjG | b0963 | b1771 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Methylglyoxal reductase, NADH-dependent; Catalyzes the NADH-dependent reduction of methylglyoxal (2- oxopropanal) in vitro. It is not known if this activity has physiological significance. Cannot use NADPH as a cosubstrate. Seems to play some role in intestinal colonization. | 0.935 |
mgsA | yqhD | b0963 | b3011 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Aldehyde reductase, NADPH-dependent; NADP-dependent ADH activity; Belongs to the iron-containing alcohol dehydrogenase family. | 0.976 |
ydjE | ydjF | b1769 | b1770 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | 0.953 |
ydjE | ydjG | b1769 | b1771 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Methylglyoxal reductase, NADH-dependent; Catalyzes the NADH-dependent reduction of methylglyoxal (2- oxopropanal) in vitro. It is not known if this activity has physiological significance. Cannot use NADPH as a cosubstrate. Seems to play some role in intestinal colonization. | 0.840 |
ydjE | ydjH | b1769 | b1772 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative kinase; Belongs to the carbohydrate kinase PfkB family. | 0.947 |
ydjE | ydjI | b1769 | b1773 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative aldolase. | 0.935 |
ydjE | ydjJ | b1769 | b1774 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative oxidoreductase. | 0.875 |
ydjE | ydjK | b1769 | b1775 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative MFS sugar transporter, membrane protein; Putative transport protein. | 0.427 |
ydjE | ydjL | b1769 | b1776 | Putative MFS sugar transporter, membrane protein; Putative transport protein. | Putative Zn-dependent NAD(P)-binding oxidoreductase. | 0.784 |
ydjF | ydjE | b1770 | b1769 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative MFS sugar transporter, membrane protein; Putative transport protein. | 0.953 |
ydjF | ydjG | b1770 | b1771 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Methylglyoxal reductase, NADH-dependent; Catalyzes the NADH-dependent reduction of methylglyoxal (2- oxopropanal) in vitro. It is not known if this activity has physiological significance. Cannot use NADPH as a cosubstrate. Seems to play some role in intestinal colonization. | 0.813 |
ydjF | ydjH | b1770 | b1772 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative kinase; Belongs to the carbohydrate kinase PfkB family. | 0.954 |
ydjF | ydjI | b1770 | b1773 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative aldolase. | 0.954 |
ydjF | ydjJ | b1770 | b1774 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative oxidoreductase. | 0.893 |
ydjF | ydjK | b1770 | b1775 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative MFS sugar transporter, membrane protein; Putative transport protein. | 0.935 |
ydjF | ydjL | b1770 | b1776 | Putative DEOR-type transcriptional regulator; Protein involved in transcription and regulation of transcription, DNA-dependent. | Putative Zn-dependent NAD(P)-binding oxidoreductase. | 0.838 |